'One way to say it is that depression, rage, and other problematic emotions are always caused by sin; however, the sin is not necessarily that of the individual. Our bodies, designed by God in God's likeness, experience crippling fear, depressoion or rgae because they inhabit a sinful world. My own sin may cause me to become depressed, but so may the ways in which I am sinned against. To make it even more complicated, my depression may be caused by a combination of my own sin, the sins which have been committed against me and the general sin of a fallen world which gave me faulty genes.'
Michael Mangis, Signature Sins, p.129.